Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
Gene | RET |
Variant | Q781R |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | RET Q781R lies within the protein kinase domain of the Ret protein (UniProt.org). Q781R has been identified in the scientific literature (PMID: 21422198, PMID: 23240926), but has not been biochemically characterized and therefore, its effect on Ret protein function is unknown (PubMed, Feb 2024). |
Associated Drug Resistance | |
Category Variants Paths |
RET mutant RET Q781R |
Transcript | NM_020975.6 |
gDNA | chr10:g.43118430A>G |
cDNA | c.2342A>G |
Protein | p.Q781R |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
NM_020630.5 | chr10:g.43118430A>G | c.2342A>G | p.Q781R | RefSeq | GRCh38/hg38 |
NM_001406760.1 | chr10:g.43118430A>G | c.2342A>G | p.Q781R | RefSeq | GRCh38/hg38 |
NM_020975.6 | chr10:g.43118430A>G | c.2342A>G | p.Q781R | RefSeq | GRCh38/hg38 |
NM_001406744.1 | chr10:g.43118430A>G | c.2342A>G | p.Q781R | RefSeq | GRCh38/hg38 |
NM_020975.5 | chr10:g.43118430A>G | c.2342A>G | p.Q781R | RefSeq | GRCh38/hg38 |
NM_020630.7 | chr10:g.43118430A>G | c.2342A>G | p.Q781R | RefSeq | GRCh38/hg38 |
NM_020975 | chr10:g.43118430A>G | c.2342A>G | p.Q781R | RefSeq | GRCh38/hg38 |
NM_020630 | chr10:g.43118430A>G | c.2342A>G | p.Q781R | RefSeq | GRCh38/hg38 |
NM_001406743.1 | chr10:g.43118430A>G | c.2342A>G | p.Q781R | RefSeq | GRCh38/hg38 |
NM_001406781.1 | chr10:g.43129569A>G | c.2342A>G | p.Q781R | RefSeq | GRCh38/hg38 |
NM_001406759.1 | chr10:g.43118430A>G | c.2342A>G | p.Q781R | RefSeq | GRCh38/hg38 |
Molecular Profile | Protein Effect | Treatment Approaches |
---|---|---|
RET Q781R | unknown |