BRIP1 T686A
Gene Variant Detail

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Gene BRIP1
Variant T686A
Impact List missense
Protein Effect unknown
Gene Variant Descriptions BRIP1 T686A does not lie within any known functional domains of the Brip1 protein (UniProt.org). T686A has been identified in sequencing studies (PMID: 19935797, PMID: 26921362), but has not been biochemically characterized and therefore, its effect on Brip1 protein function is unknown (PubMed, Feb 2026).
Associated Drug Resistance
Category Variants Paths

BRIP1 mutant BRIP1 T686A

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Transcript NM_032043.3
gDNA chr17:g.61776442T>C
cDNA c.2056A>G
Protein p.T686A
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_047436901.1 chr17:g.61776442T>C c.2056A>G p.T686A RefSeq GRCh38/hg38
XM_011525337 chr17:g.61744492T>C c.2056A>G p.T686A RefSeq GRCh38/hg38
XM_011525335 chr17:g.61776442T>C c.2056A>G p.T686A RefSeq GRCh38/hg38
XM_047436892.1 chr17:g.61776442T>C c.2056A>G p.T686A RefSeq GRCh38/hg38
XM_047436896.1 chr17:g.61776442T>C c.2056A>G p.T686A RefSeq GRCh38/hg38
NM_032043.3 chr17:g.61776442T>C c.2056A>G p.T686A RefSeq GRCh38/hg38
NM_032043 chr17:g.61776442T>C c.2056A>G p.T686A RefSeq GRCh38/hg38
XM_047436900.1 chr17:g.61776442T>C c.2056A>G p.T686A RefSeq GRCh38/hg38
NM_032043.2 chr17:g.61776442T>C c.2056A>G p.T686A RefSeq GRCh38/hg38
XM_047436897.1 chr17:g.61776442T>C c.2056A>G p.T686A RefSeq GRCh38/hg38
XM_011525335.3 chr17:g.61776442T>C c.2056A>G p.T686A RefSeq GRCh38/hg38
XM_011525335.4 chr17:g.61776442T>C c.2056A>G p.T686A RefSeq GRCh38/hg38
XM_011525337.2 chr17:g.61744492T>C c.2056A>G p.T686A RefSeq GRCh38/hg38
XM_047436899.1 chr17:g.61776442T>C c.2056A>G p.T686A RefSeq GRCh38/hg38
XM_047436891.1 chr17:g.61776442T>C c.2056A>G p.T686A RefSeq GRCh38/hg38

Filtering

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  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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  • Click on any column header arrows to sort by that column
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References