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| Gene | MSH3 |
| Variant | loss |
| Impact List | unknown |
| Protein Effect | loss of function |
| Gene Variant Descriptions | MSH3 loss indicates loss of the MSH3 gene, mRNA, and protein. |
| Associated Drug Resistance | |
| Category Variants Paths |
MSH3 mutant MSH3 inact mut MSH3 loss |
| Molecular Profile | Protein Effect | Treatment Approaches |
|---|---|---|
| MSH3 loss | loss of function | |
| MLH1 loss MSH3 loss |