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Gene BRAF
Variant D380H
Impact List missense
Protein Effect no effect - predicted
Gene Variant Descriptions BRAF D380H does not lie within any known functional domains of the Braf protein (UniProt.org). D380H has not been biochemically characterized, but results in similar cell proliferation and viability levels as wild-type Braf in culture (PMID: 29533785), and therefore, is predicted to have no effect on Braf protein function.
Associated Drug Resistance
Category Variants Paths

BRAF mutant BRAF D380H

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Transcript NM_004333.6
gDNA chr7:g.140794310C>G
cDNA c.1138G>C
Protein p.D380H
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001378469.1 chr7:g.140794310C>G c.1138G>C p.D380H RefSeq GRCh38/hg38
NM_001374258.1 chr7:g.140794310C>G c.1138G>C p.D380H RefSeq GRCh38/hg38
NM_001378474.1 chr7:g.140794310C>G c.1138G>C p.D380H RefSeq GRCh38/hg38
XM_017012559 chr7:g.140794310C>G c.1138G>C p.D380H RefSeq GRCh38/hg38
NM_001378468.1 chr7:g.140794310C>G c.1138G>C p.D380H RefSeq GRCh38/hg38
XM_017012559.2 chr7:g.140794310C>G c.1138G>C p.D380H RefSeq GRCh38/hg38
XM_047420767.1 chr7:g.140794310C>G c.1138G>C p.D380H RefSeq GRCh38/hg38
XM_017012559.1 chr7:g.140794310C>G c.1138G>C p.D380H RefSeq GRCh38/hg38
NM_004333.6 chr7:g.140794310C>G c.1138G>C p.D380H RefSeq GRCh38/hg38
NM_004333.5 chr7:g.140794310C>G c.1138G>C p.D380H RefSeq GRCh38/hg38
NM_004333 chr7:g.140794310C>G c.1138G>C p.D380H RefSeq GRCh38/hg38
XM_005250045 chr7:g.140794310C>G c.1138G>C p.D380H RefSeq GRCh38/hg38
XM_017012558.1 chr7:g.140794310C>G c.1138G>C p.D380H RefSeq GRCh38/hg38
NM_001378471.1 chr7:g.140794310C>G c.1138G>C p.D380H RefSeq GRCh38/hg38
NM_001374244.1 chr7:g.140794310C>G c.1138G>C p.D380H RefSeq GRCh38/hg38
XM_047420769.1 chr7:g.140794310C>G c.1138G>C p.D380H RefSeq GRCh38/hg38
XM_017012558 chr7:g.140794310C>G c.1138G>C p.D380H RefSeq GRCh38/hg38
XM_047420768.1 chr7:g.140794310C>G c.1138G>C p.D380H RefSeq GRCh38/hg38
NM_001354609.2 chr7:g.140794310C>G c.1138G>C p.D380H RefSeq GRCh38/hg38
NM_001354609.1 chr7:g.140794310C>G c.1138G>C p.D380H RefSeq GRCh38/hg38

Filtering

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  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Protein Effect Treatment Approaches
BRAF D380H no effect - predicted