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Gene BRAF
Variant R188T
Impact List missense
Protein Effect no effect - predicted
Gene Variant Descriptions BRAF R188T lies within the RBD domain of the Braf protein (UniProt.org). R188T has not been biochemically characterized, but results in similar cell proliferation and viability levels as wild-type Braf in culture (PMID: 29533785), and therefore, is predicted to have no effect on Braf protein function.
Associated Drug Resistance
Category Variants Paths

BRAF mutant BRAF R188T

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Transcript NM_004333.6
gDNA chr7:g.140808937C>G
cDNA c.563G>C
Protein p.R188T
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_017012559.1 chr7:g.140808937C>G c.563G>C p.R188T RefSeq GRCh38/hg38
XM_047420769.1 chr7:g.140808937C>G c.563G>C p.R188T RefSeq GRCh38/hg38
XM_017012559 chr7:g.140808937C>G c.563G>C p.R188T RefSeq GRCh38/hg38
NM_001378467.1 chr7:g.140808937C>G c.563G>C p.R188T RefSeq GRCh38/hg38
NM_001374244.1 chr7:g.140808937C>G c.563G>C p.R188T RefSeq GRCh38/hg38
NM_001378469.1 chr7:g.140808937C>G c.563G>C p.R188T RefSeq GRCh38/hg38
NM_001378474.1 chr7:g.140808937C>G c.563G>C p.R188T RefSeq GRCh38/hg38
XM_047420767.1 chr7:g.140808937C>G c.563G>C p.R188T RefSeq GRCh38/hg38
XM_047420768.1 chr7:g.140808937C>G c.563G>C p.R188T RefSeq GRCh38/hg38
XM_017012558 chr7:g.140808937C>G c.563G>C p.R188T RefSeq GRCh38/hg38
XM_005250045 chr7:g.140808937C>G c.563G>C p.R188T RefSeq GRCh38/hg38
NM_004333.5 chr7:g.140808937C>G c.563G>C p.R188T RefSeq GRCh38/hg38
NM_004333 chr7:g.140808937C>G c.563G>C p.R188T RefSeq GRCh38/hg38
XM_017012558.1 chr7:g.140808937C>G c.563G>C p.R188T RefSeq GRCh38/hg38
NM_004333.6 chr7:g.140808937C>G c.563G>C p.R188T RefSeq GRCh38/hg38
NM_001378471.1 chr7:g.140808937C>G c.563G>C p.R188T RefSeq GRCh38/hg38
NM_001374258.1 chr7:g.140808937C>G c.563G>C p.R188T RefSeq GRCh38/hg38
XM_047420770.1 chr7:g.140783058C>G c.563G>C p.R188T RefSeq GRCh38/hg38
NM_001354609.2 chr7:g.140808937C>G c.563G>C p.R188T RefSeq GRCh38/hg38
NM_001354609.1 chr7:g.140808937C>G c.563G>C p.R188T RefSeq GRCh38/hg38
XM_017012559.2 chr7:g.140808937C>G c.563G>C p.R188T RefSeq GRCh38/hg38
NM_001378468.1 chr7:g.140808937C>G c.563G>C p.R188T RefSeq GRCh38/hg38

Filtering

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  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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  • Click on any column header arrows to sort by that column
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Molecular Profile Protein Effect Treatment Approaches
BRAF R188T no effect - predicted