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RET D631_R635delinsG - Gene Variant Detail

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Gene RET
Variant D631_R635delinsG
Impact List indel
Protein Effect unknown
Gene Variant Descriptions RET D631_R635delinsG results in a deletion of five amino acids in the extracellular domain of the Ret protein from amino acids 631 to 635, combined with the insertion of a glycine (G) at the same site (UniProt.org). D631_R635delinsG has been identified in the scientific literature (PMID: 29657135), but has not been biochemically characterized and therefore, its effect on Ret protein function is unknown (PubMed, Feb 2025).
Associated Drug Resistance
Category Variants Paths

RET mutant RET D631_R635delinsG

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Transcript NM_020975.6
gDNA chr10:g.43114492_43114503del12
cDNA c.1892_1903del12
Protein p.D631_R635delinsG
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_020630.7 chr10:g.43114492_43114503del12 c.1892_1903del12 p.D631_R635delinsG RefSeq GRCh38/hg38
NM_020630 chr10:g.43114492_43114503del12 c.1892_1903del12 p.D631_R635delinsG RefSeq GRCh38/hg38
NM_020630.5 chr10:g.43114492_43114503del12 c.1892_1903del12 p.D631_R635delinsG RefSeq GRCh38/hg38
NM_001406743.1 chr10:g.43114492_43114503del12 c.1892_1903del12 p.D631_R635delinsG RefSeq GRCh38/hg38
NM_001406744.1 chr10:g.43114492_43114503del12 c.1892_1903del12 p.D631_R635delinsG RefSeq GRCh38/hg38
NM_001406759.1 chr10:g.43114492_43114503del12 c.1892_1903del12 p.D631_R635delinsG RefSeq GRCh38/hg38
NM_020975.6 chr10:g.43114492_43114503del12 c.1892_1903del12 p.D631_R635delinsG RefSeq GRCh38/hg38
NM_020975 chr10:g.43114492_43114503del12 c.1892_1903del12 p.D631_R635delinsG RefSeq GRCh38/hg38
NM_020975.5 chr10:g.43114492_43114503del12 c.1892_1903del12 p.D631_R635delinsG RefSeq GRCh38/hg38
NM_001406760.1 chr10:g.43114492_43114503del12 c.1892_1903del12 p.D631_R635delinsG RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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  • Click on any column header arrows to sort by that column
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Molecular Profile Protein Effect Treatment Approaches
RET D631_R635delinsG unknown
RET L629P RET D631_R635delinsG RET V637R