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Gene | RET |
Variant | V637R |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | RET V637R lies within the transmembrane domain of the Ret protein (UniProt.org). V637R has been identified in the scientific literature (PMID: 29657135), but has not been biochemically characterized and therefore, its effect on Ret protein function is unknown (PubMed, Feb 2025). |
Associated Drug Resistance | |
Category Variants Paths |
RET mutant RET V637R |
Transcript | NM_020975.6 |
gDNA | chr10:g.43114509_43114510delGTinsAG |
cDNA | c.1909_1910delGTinsAG |
Protein | p.V637R |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |