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Gene RET
Variant V637R
Impact List missense
Protein Effect unknown
Gene Variant Descriptions RET V637R lies within the transmembrane domain of the Ret protein (UniProt.org). V637R has been identified in the scientific literature (PMID: 29657135), but has not been biochemically characterized and therefore, its effect on Ret protein function is unknown (PubMed, Feb 2024).
Associated Drug Resistance
Category Variants Paths

RET mutant RET V637R

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Transcript NM_020975.6
gDNA chr10:g.43114509_43114510delGTinsAG
cDNA c.1909_1910delGTinsAG
Protein p.V637R
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_020975.5 chr10:g.43114509_43114510delGTinsAG c.1909_1910delGTinsAG p.V637R RefSeq GRCh38/hg38
NM_020630.5 chr10:g.43114509_43114510delGTinsAG c.1909_1910delGTinsAG p.V637R RefSeq GRCh38/hg38
NM_020975 chr10:g.43114509_43114510delGTinsAG c.1909_1910delGTinsAG p.V637R RefSeq GRCh38/hg38
NM_001406743.1 chr10:g.43114509_43114510delGTinsAG c.1909_1910delGTinsAG p.V637R RefSeq GRCh38/hg38
NM_001406760.1 chr10:g.43114509_43114510delGTinsAG c.1909_1910delGTinsAG p.V637R RefSeq GRCh38/hg38
NM_020630.7 chr10:g.43114509_43114510delGTinsAG c.1909_1910delGTinsAG p.V637R RefSeq GRCh38/hg38
NM_020975.6 chr10:g.43114509_43114510delGTinsAG c.1909_1910delGTinsAG p.V637R RefSeq GRCh38/hg38
NM_001406744.1 chr10:g.43114509_43114510delGTinsAG c.1909_1910delGTinsAG p.V637R RefSeq GRCh38/hg38
NM_001406759.1 chr10:g.43114509_43114510delGTinsAG c.1909_1910delGTinsAG p.V637R RefSeq GRCh38/hg38
NM_020630 chr10:g.43114509_43114510delGTinsAG c.1909_1910delGTinsAG p.V637R RefSeq GRCh38/hg38
NM_001406768.1 chr10:g.43116620_43116621delGTinsCG c.1909_1910delGTinsCG p.V637R RefSeq GRCh38/hg38

Filtering

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  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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  • Click on any column header arrows to sort by that column
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Molecular Profile Protein Effect Treatment Approaches
RET L629P RET D631_R635delinsG RET V637R
RET V637R unknown