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Gene RET
Variant L629P
Impact List missense
Protein Effect unknown
Gene Variant Descriptions RET L629P lies within the extracellular domain of the Ret protein (UniProt.org). L629P has been identified in the scientific literature (PMID: 29657135), but has not been biochemically characterized and therefore, its effect on Ret protein function is unknown (PubMed, Feb 2024).
Associated Drug Resistance
Category Variants Paths

RET mutant RET L629P

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Transcript NM_020975.6
gDNA chr10:g.43114486T>C
cDNA c.1886T>C
Protein p.L629P
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_020975.6 chr10:g.43114486T>C c.1886T>C p.L629P RefSeq GRCh38/hg38
NM_001406759.1 chr10:g.43114486T>C c.1886T>C p.L629P RefSeq GRCh38/hg38
NM_020630.5 chr10:g.43114486T>C c.1886T>C p.L629P RefSeq GRCh38/hg38
NM_020975.5 chr10:g.43114486T>C c.1886T>C p.L629P RefSeq GRCh38/hg38
NM_020630 chr10:g.43114486T>C c.1886T>C p.L629P RefSeq GRCh38/hg38
NM_001406743.1 chr10:g.43114486T>C c.1886T>C p.L629P RefSeq GRCh38/hg38
NM_001406760.1 chr10:g.43114486T>C c.1886T>C p.L629P RefSeq GRCh38/hg38
NM_001406744.1 chr10:g.43114486T>C c.1886T>C p.L629P RefSeq GRCh38/hg38
NM_020630.7 chr10:g.43114486T>C c.1886T>C p.L629P RefSeq GRCh38/hg38
NM_020975 chr10:g.43114486T>C c.1886T>C p.L629P RefSeq GRCh38/hg38

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References