CD274 negative
Gene Variant Detail

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Gene CD274
Variant negative
Impact List unknown
Protein Effect loss of function
Gene Variant Descriptions CD274 negative indicates a lack of expression of the CD274 mRNA and/or protein.
Associated Drug Resistance
Category Variants Paths

CD274 mutant CD274 inact mut CD274 negative

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No Variant Reference Transcript is Available.
No transcript is Available.

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT04468061 Phase II Sacituzumab govitecan-hziy Pembrolizumab + Sacituzumab govitecan-hziy Sacituzumab Govitecan +/- Pembrolizumab in Metastatic TNBC Recruiting USA 0
NCT05491226 Phase II Axatilimab + Pembrolizumab Reinvigorating TNBC Response to Immunotherapy With Combination Myeloid Inhibition and Radiation Active, not recruiting USA 0
NCT07299409 Phase II Sacituzumab govitecan-hziy First-Line Sacituzumab Govitecan in Advanced Untreated Triple-Negative Breast Cancer Patients. Not yet recruiting CAN 0
NCT04356729 Phase II Atezolizumab + Bevacizumab A Phase II Trial of PD-L1 Therapy Combined with Anti-VEGF Therapy in Unresectable or Metastatic Melanoma Active, not recruiting USA 0
NCT04837209 Phase II Dostarlimab-gxly + Niraparib Radiation, Immunotherapy and PARP Inhibitor in Triple Negative Breast Cancer (NADiR) Active, not recruiting USA 0