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Gene RET
Variant A807V
Impact List missense
Protein Effect unknown
Gene Variant Descriptions RET A807V lies within the protein kinase domain of the Ret protein (UniProt.org). A807V has been demonstrated to confer drug resistance in the context of KIF5B-RET in culture (PMID: 29908090), but has not been biochemically characterized and therefore, its effect on Ret protein function is unknown (PubMed, Aug 2024).
Associated Drug Resistance Y
Category Variants Paths

RET mutant RET A807V

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Transcript NM_020975.6
gDNA chr10:g.43119558C>T
cDNA c.2420C>T
Protein p.A807V
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001406779.1 chr10:g.43128241C>T c.2420C>T p.A807V RefSeq GRCh38/hg38
NM_020630 chr10:g.43119558C>T c.2420C>T p.A807V RefSeq GRCh38/hg38
NM_001406760.1 chr10:g.43119558C>T c.2420C>T p.A807V RefSeq GRCh38/hg38
NM_001406744.1 chr10:g.43119558C>T c.2420C>T p.A807V RefSeq GRCh38/hg38
NM_020630.5 chr10:g.43119558C>T c.2420C>T p.A807V RefSeq GRCh38/hg38
NM_020975 chr10:g.43119558C>T c.2420C>T p.A807V RefSeq GRCh38/hg38
NM_001406759.1 chr10:g.43119558C>T c.2420C>T p.A807V RefSeq GRCh38/hg38
NM_001406743.1 chr10:g.43119558C>T c.2420C>T p.A807V RefSeq GRCh38/hg38
NM_020975.5 chr10:g.43119558C>T c.2420C>T p.A807V RefSeq GRCh38/hg38
NM_020630.7 chr10:g.43119558C>T c.2420C>T p.A807V RefSeq GRCh38/hg38
NM_020975.6 chr10:g.43119558C>T c.2420C>T p.A807V RefSeq GRCh38/hg38
NM_001406780.1 chr10:g.43128241C>T c.2420C>T p.A807V RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries