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Gene RET
Variant M1064T
Impact List missense
Protein Effect unknown
Gene Variant Descriptions RET M1064T lies within the cytoplasmic domain of the Ret protein (UniProt.org). M1064T does not affect the function of a concurrent activating RET mutation (C634R) in culture (PMID: 9502784), but has not been individually characterized and therefore, its effect on Ret protein function is unknown (PubMed, Aug 2024).
Associated Drug Resistance
Category Variants Paths

RET mutant RET M1064T

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Transcript NM_020975.6
gDNA chr10:g.43128115T>C
cDNA c.3191T>C
Protein p.M1064T
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_020975 chr10:g.43128115T>C c.3191T>C p.M1064T RefSeq GRCh38/hg38
NM_020975.5 chr10:g.43128115T>C c.3191T>C p.M1064T RefSeq GRCh38/hg38
NM_001406763.1 chr10:g.43128250T>C c.3191T>C p.M1064T RefSeq GRCh38/hg38
NM_001406743.1 chr10:g.43128115T>C c.3191T>C p.M1064T RefSeq GRCh38/hg38
NM_020975.6 chr10:g.43128115T>C c.3191T>C p.M1064T RefSeq GRCh38/hg38

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  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References