Gene Variant Detail

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Gene BRAF
Variant S363F
Impact List missense
Protein Effect unknown
Gene Variant Descriptions BRAF S363F does not lie within any known functional domains of the Braf protein (UniProt.org). S363F has been identified in the scientific literature (PMID: 29903896), but has not been biochemically characterized and therefore, its effect on Braf protein function is unknown (PubMed, Sep 2024).
Associated Drug Resistance
Category Variants Paths

BRAF mutant BRAF S363F

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Transcript NM_004333.6
gDNA chr7:g.140794360G>A
cDNA c.1088C>T
Protein p.S363F
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_047420767.1 chr7:g.140794360G>A c.1088C>T p.S363F RefSeq GRCh38/hg38
XM_047420769.1 chr7:g.140794360G>A c.1088C>T p.S363F RefSeq GRCh38/hg38
NM_001378468.1 chr7:g.140794360G>A c.1088C>T p.S363F RefSeq GRCh38/hg38
NM_001354609.2 chr7:g.140794360G>A c.1088C>T p.S363F RefSeq GRCh38/hg38
NM_001374244.1 chr7:g.140794360G>A c.1088C>T p.S363F RefSeq GRCh38/hg38
XM_017012559 chr7:g.140794360G>A c.1088C>T p.S363F RefSeq GRCh38/hg38
NM_001374258.1 chr7:g.140794360G>A c.1088C>T p.S363F RefSeq GRCh38/hg38
NM_004333 chr7:g.140794360G>A c.1088C>T p.S363F RefSeq GRCh38/hg38
NM_004333.5 chr7:g.140794360G>A c.1088C>T p.S363F RefSeq GRCh38/hg38
NM_004333.6 chr7:g.140794360G>A c.1088C>T p.S363F RefSeq GRCh38/hg38
XM_017012559.1 chr7:g.140794360G>A c.1088C>T p.S363F RefSeq GRCh38/hg38
NM_001354609.1 chr7:g.140794360G>A c.1088C>T p.S363F RefSeq GRCh38/hg38
XM_017012558 chr7:g.140794360G>A c.1088C>T p.S363F RefSeq GRCh38/hg38
NM_001378471.1 chr7:g.140794360G>A c.1088C>T p.S363F RefSeq GRCh38/hg38
XM_047420768.1 chr7:g.140794360G>A c.1088C>T p.S363F RefSeq GRCh38/hg38
XM_017012559.2 chr7:g.140794360G>A c.1088C>T p.S363F RefSeq GRCh38/hg38
NM_001378469.1 chr7:g.140794360G>A c.1088C>T p.S363F RefSeq GRCh38/hg38
XM_017012558.1 chr7:g.140794360G>A c.1088C>T p.S363F RefSeq GRCh38/hg38
NM_001378474.1 chr7:g.140794360G>A c.1088C>T p.S363F RefSeq GRCh38/hg38
XM_005250045 chr7:g.140794360G>A c.1088C>T p.S363F RefSeq GRCh38/hg38

Filtering

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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References