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Gene | BRAF |
Variant | Q257X |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | BRAF Q257X indicates any BRAF missense mutation that results in replacement of the glutamine (Q) at amino acid 257 by a different amino acid. |
Associated Drug Resistance | |
Category Variants Paths |
BRAF mutant BRAF Q257X |
Transcript | NM_004333.6 |
gDNA | chr7:g.140801501_140801503 |
cDNA | c.769_771 |
Protein | p.Q257 |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
NM_001354609.2 | chr7:g.140801501_140801503 | c.769_771 | p.Q257 | RefSeq | GRCh38/hg38 |
NM_001378471.1 | chr7:g.140801501_140801503 | c.769_771 | p.Q257 | RefSeq | GRCh38/hg38 |
NM_001378468.1 | chr7:g.140801501_140801503 | c.769_771 | p.Q257 | RefSeq | GRCh38/hg38 |
NM_001374258.1 | chr7:g.140801501_140801503 | c.769_771 | p.Q257 | RefSeq | GRCh38/hg38 |
NM_001354609.1 | chr7:g.140801501_140801503 | c.769_771 | p.Q257 | RefSeq | GRCh38/hg38 |
XM_017012559.1 | chr7:g.140801501_140801503 | c.769_771 | p.Q257 | RefSeq | GRCh38/hg38 |
NM_004333.5 | chr7:g.140801501_140801503 | c.769_771 | p.Q257 | RefSeq | GRCh38/hg38 |
NM_001378469.1 | chr7:g.140801501_140801503 | c.769_771 | p.Q257 | RefSeq | GRCh38/hg38 |
NM_001378474.1 | chr7:g.140801501_140801503 | c.769_771 | p.Q257 | RefSeq | GRCh38/hg38 |
NM_004333.6 | chr7:g.140801501_140801503 | c.769_771 | p.Q257 | RefSeq | GRCh38/hg38 |
NM_001374244.1 | chr7:g.140801501_140801503 | c.769_771 | p.Q257 | RefSeq | GRCh38/hg38 |
XM_047420769.1 | chr7:g.140801501_140801503 | c.769_771 | p.Q257 | RefSeq | GRCh38/hg38 |
XM_047420767.1 | chr7:g.140801501_140801503 | c.769_771 | p.Q257 | RefSeq | GRCh38/hg38 |
XM_047420768.1 | chr7:g.140801501_140801503 | c.769_771 | p.Q257 | RefSeq | GRCh38/hg38 |
XM_017012558.1 | chr7:g.140801501_140801503 | c.769_771 | p.Q257 | RefSeq | GRCh38/hg38 |
XM_017012559.2 | chr7:g.140801501_140801503 | c.769_771 | p.Q257 | RefSeq | GRCh38/hg38 |
Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
---|---|---|---|---|---|---|
NCT03839342 | Phase II | Binimetinib + Encorafenib | Binimetinib and Encorafenib for the Treatment of Advanced Solid Tumors With Non-V600E BRAF Mutations (BEAVER) | Active, not recruiting | CAN | 0 |