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Gene BRAF
Variant G464X
Impact List missense
Protein Effect unknown
Gene Variant Descriptions BRAF G464X indicates any BRAF missense mutation that results in replacement of the glycine (G) at amino acid 464 by a different amino acid.
Associated Drug Resistance
Category Variants Paths

BRAF mutant BRAF G464X

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Transcript NM_004333.6
gDNA chr7:g.140781616_140781618
cDNA c.1390_1392
Protein p.G464
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_047420769.1 chr7:g.140781616_140781618 c.1390_1392 p.G464 RefSeq GRCh38/hg38
NM_001378474.1 chr7:g.140781616_140781618 c.1390_1392 p.G464 RefSeq GRCh38/hg38
NM_001378468.1 chr7:g.140781616_140781618 c.1390_1392 p.G464 RefSeq GRCh38/hg38
NM_004333.5 chr7:g.140781616_140781618 c.1390_1392 p.G464 RefSeq GRCh38/hg38
NM_001354609.1 chr7:g.140781616_140781618 c.1390_1392 p.G464 RefSeq GRCh38/hg38
NM_004333.6 chr7:g.140781616_140781618 c.1390_1392 p.G464 RefSeq GRCh38/hg38
NM_001354609.2 chr7:g.140781616_140781618 c.1390_1392 p.G464 RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT03839342 Phase II Binimetinib + Encorafenib Binimetinib and Encorafenib for the Treatment of Advanced Solid Tumors With Non-V600E BRAF Mutations (BEAVER) Active, not recruiting CAN 0