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Gene | BRAF |
Variant | G464X |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | BRAF G464X indicates any BRAF missense mutation that results in replacement of the glycine (G) at amino acid 464 by a different amino acid. |
Associated Drug Resistance | |
Category Variants Paths |
BRAF mutant BRAF G464X |
Transcript | NM_004333.6 |
gDNA | chr7:g.140781616_140781618 |
cDNA | c.1390_1392 |
Protein | p.G464 |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
XM_047420769.1 | chr7:g.140781616_140781618 | c.1390_1392 | p.G464 | RefSeq | GRCh38/hg38 |
NM_004333.5 | chr7:g.140781616_140781618 | c.1390_1392 | p.G464 | RefSeq | GRCh38/hg38 |
NM_004333.6 | chr7:g.140781616_140781618 | c.1390_1392 | p.G464 | RefSeq | GRCh38/hg38 |
NM_001378474.1 | chr7:g.140781616_140781618 | c.1390_1392 | p.G464 | RefSeq | GRCh38/hg38 |
NM_001378468.1 | chr7:g.140781616_140781618 | c.1390_1392 | p.G464 | RefSeq | GRCh38/hg38 |
NM_001354609.1 | chr7:g.140781616_140781618 | c.1390_1392 | p.G464 | RefSeq | GRCh38/hg38 |
NM_001354609.2 | chr7:g.140781616_140781618 | c.1390_1392 | p.G464 | RefSeq | GRCh38/hg38 |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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