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Gene BRAF
Variant G466X
Impact List missense
Protein Effect unknown
Gene Variant Descriptions BRAF G466X indicates any BRAF missense mutation that results in replacement of the glycine (G) at amino acid 466 by a different amino acid.
Associated Drug Resistance
Category Variants Paths

BRAF mutant BRAF G466X

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Transcript NM_004333.6
gDNA chr7:g.140781610_140781612
cDNA c.1396_1398
Protein p.G466
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001378471.1 chr7:g.140777999_140778001 c.1396_1398 p.G466 RefSeq GRCh38/hg38
NM_001378472.1 chr7:g.140777052_140777054 c.1396_1398 p.G466 RefSeq GRCh38/hg38
XM_047420766.1 chr7:g.140778074_140781576 c.1396_1398 p.G466 RefSeq GRCh38/hg38
XM_047420769.1 chr7:g.140781610_140781612 c.1396_1398 p.G466 RefSeq GRCh38/hg38
NM_001354609.2 chr7:g.140781610_140781612 c.1396_1398 p.G466 RefSeq GRCh38/hg38
NM_004333.5 chr7:g.140781610_140781612 c.1396_1398 p.G466 RefSeq GRCh38/hg38
NM_001378468.1 chr7:g.140781610_140781612 c.1396_1398 p.G466 RefSeq GRCh38/hg38
NM_001354609.1 chr7:g.140781610_140781612 c.1396_1398 p.G466 RefSeq GRCh38/hg38
NM_001378473.1 chr7:g.140777052_140777054 c.1396_1398 p.G466 RefSeq GRCh38/hg38
NM_004333.6 chr7:g.140781610_140781612 c.1396_1398 p.G466 RefSeq GRCh38/hg38
NM_001378474.1 chr7:g.140781610_140781612 c.1396_1398 p.G466 RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT03839342 Phase II Binimetinib + Encorafenib Binimetinib and Encorafenib for the Treatment of Advanced Solid Tumors With Non-V600E BRAF Mutations (BEAVER) Active, not recruiting CAN 0