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Gene BRAF
Variant N581X
Impact List missense
Protein Effect unknown
Gene Variant Descriptions BRAF N581X indicates any BRAF missense mutation that results in replacement of the asparagine (N) at amino acid 581 by a different amino acid.
Associated Drug Resistance
Category Variants Paths

BRAF mutant BRAF N581X

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Transcript NM_004333.6
gDNA chr7:g.140753392_140754187
cDNA c.1741_1743
Protein p.N581
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001354609.2 chr7:g.140753392_140754187 c.1741_1743 p.N581 RefSeq GRCh38/hg38
NM_001378468.1 chr7:g.140753392_140754187 c.1741_1743 p.N581 RefSeq GRCh38/hg38
NM_001378474.1 chr7:g.140753392_140754187 c.1741_1743 p.N581 RefSeq GRCh38/hg38
NM_001354609.1 chr7:g.140753392_140754187 c.1741_1743 p.N581 RefSeq GRCh38/hg38
NM_004333.6 chr7:g.140753392_140754187 c.1741_1743 p.N581 RefSeq GRCh38/hg38
NM_004333.5 chr7:g.140753392_140754187 c.1741_1743 p.N581 RefSeq GRCh38/hg38

Filtering

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  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT03839342 Phase II Binimetinib + Encorafenib Binimetinib and Encorafenib for the Treatment of Advanced Solid Tumors With Non-V600E BRAF Mutations (BEAVER) Active, not recruiting CAN 0