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| Gene | BRAF |
| Variant | P731T |
| Impact List | missense |
| Protein Effect | unknown |
| Gene Variant Descriptions | BRAF P731T does not lie within any known functional domains of the Braf protein (UniProt.org). P731T has been identified in the scientific literature (PMID: 29320312), but has not been biochemically characterized and therefore, its effect on Braf protein function is unknown (PubMed, Jun 2025). |
| Associated Drug Resistance | |
| Category Variants Paths |
BRAF mutant BRAF P731T |
| Transcript | NM_004333.6 |
| gDNA | chr7:g.140734707G>T |
| cDNA | c.2191C>A |
| Protein | p.P731T |
| Source Database | RefSeq |
| Genome Build | GRCh38/hg38 |
| Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
|---|---|---|---|---|---|
| NM_004333.5 | chr7:g.140734707G>T | c.2191C>A | p.P731T | RefSeq | GRCh38/hg38 |
| NM_004333.6 | chr7:g.140734707G>T | c.2191C>A | p.P731T | RefSeq | GRCh38/hg38 |
| NM_001354609.2 | chr7:g.140734707G>T | c.2191C>A | p.P731T | RefSeq | GRCh38/hg38 |
| NM_004333 | chr7:g.140734707G>T | c.2191C>A | p.P731T | RefSeq | GRCh38/hg38 |
| NM_001354609.1 | chr7:g.140734707G>T | c.2191C>A | p.P731T | RefSeq | GRCh38/hg38 |
| XM_005250045 | chr7:g.140734707G>T | c.2191C>A | p.P731T | RefSeq | GRCh38/hg38 |
| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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