Gene Variant Detail

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Gene BRAF
Variant P367L
Impact List missense
Protein Effect unknown
Gene Variant Descriptions BRAF P367L does not lie within any known functional domains of the Braf protein (UniProt.org). P367L has been identified in sequencing studies (PMID: 26317466), but has not been biochemically characterized and therefore, its effect on Braf protein function is unknown (PubMed, Sep 2024).
Associated Drug Resistance
Category Variants Paths

BRAF mutant BRAF P367X BRAF P367L

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Transcript NM_004333.6
gDNA chr7:g.140794348G>A
cDNA c.1100C>T
Protein p.P367L
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_017012558 chr7:g.140794348G>A c.1100C>T p.P367L RefSeq GRCh38/hg38
XM_047420769.1 chr7:g.140794348G>A c.1100C>T p.P367L RefSeq GRCh38/hg38
NM_001378469.1 chr7:g.140794348G>A c.1100C>T p.P367L RefSeq GRCh38/hg38
NM_001374244.1 chr7:g.140794348G>A c.1100C>T p.P367L RefSeq GRCh38/hg38
XM_005250045 chr7:g.140794348G>A c.1100C>T p.P367L RefSeq GRCh38/hg38
NM_004333 chr7:g.140794348G>A c.1100C>T p.P367L RefSeq GRCh38/hg38
XM_017012558.1 chr7:g.140794348G>A c.1100C>T p.P367L RefSeq GRCh38/hg38
XM_017012559 chr7:g.140794348G>A c.1100C>T p.P367L RefSeq GRCh38/hg38
NM_001378471.1 chr7:g.140794348G>A c.1100C>T p.P367L RefSeq GRCh38/hg38
NM_001354609.2 chr7:g.140794348G>A c.1100C>T p.P367L RefSeq GRCh38/hg38
XM_047420767.1 chr7:g.140794348G>A c.1100C>T p.P367L RefSeq GRCh38/hg38
XM_017012559.1 chr7:g.140794348G>A c.1100C>T p.P367L RefSeq GRCh38/hg38
XM_047420768.1 chr7:g.140794348G>A c.1100C>T p.P367L RefSeq GRCh38/hg38
XM_017012559.2 chr7:g.140794348G>A c.1100C>T p.P367L RefSeq GRCh38/hg38
NM_004333.6 chr7:g.140794348G>A c.1100C>T p.P367L RefSeq GRCh38/hg38
NM_004333.5 chr7:g.140794348G>A c.1100C>T p.P367L RefSeq GRCh38/hg38
NM_001354609.1 chr7:g.140794348G>A c.1100C>T p.P367L RefSeq GRCh38/hg38
NM_001374258.1 chr7:g.140794348G>A c.1100C>T p.P367L RefSeq GRCh38/hg38
NM_001378474.1 chr7:g.140794348G>A c.1100C>T p.P367L RefSeq GRCh38/hg38
NM_001378468.1 chr7:g.140794348G>A c.1100C>T p.P367L RefSeq GRCh38/hg38

Filtering

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References