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Gene | NTRK2 |
Variant | G623R |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | NTRK2 G623R lies within the protein kinase domain of the Ntrk2 protein (UniProt.org). G623R has been identified in the scientific literature (PMID: 26884591), but has not been biochemically characterized and therefore, its effect on Ntrk2 protein function is unknown (PubMed, Jul 2025). |
Associated Drug Resistance | |
Category Variants Paths |
NTRK2 mutant NTRK2 G623R |
Transcript | NM_001018064.3 |
gDNA | chr9:g.84948612G>A |
cDNA | c.1867G>A |
Protein | p.G623R |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |