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Gene RET
Variant E768N
Impact List missense
Protein Effect unknown
Gene Variant Descriptions RET E768N lies within the protein kinase domain of the Ret protein (UniProt.org). E768N has been identified in the scientific literature (PMID: 31145454), but has not been biochemically characterized and therefore, its effect on Ret protein function is unknown (PubMed, Feb 2024).
Associated Drug Resistance
Category Variants Paths

RET mutant RET E768X RET E768N

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Transcript NM_020975.6
gDNA chr10:g.43118390_43118392delGAGinsAAC
cDNA c.2302_2304delGAGinsAAC
Protein p.E768N
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_020975.6 chr10:g.43118390_43118392delGAGinsAAC c.2302_2304delGAGinsAAC p.E768N RefSeq GRCh38/hg38
NM_020630.7 chr10:g.43118390_43118392delGAGinsAAC c.2302_2304delGAGinsAAC p.E768N RefSeq GRCh38/hg38
NM_001406744.1 chr10:g.43118390_43118392delGAGinsAAC c.2302_2304delGAGinsAAC p.E768N RefSeq GRCh38/hg38
NM_020630.5 chr10:g.43118390_43118392delGAGinsAAC c.2302_2304delGAGinsAAC p.E768N RefSeq GRCh38/hg38
NM_001406774.1 chr10:g.43123696_43123698delGAGinsAAC c.2302_2304delGAGinsAAC p.E768N RefSeq GRCh38/hg38
NM_020975 chr10:g.43118390_43118392delGAGinsAAC c.2302_2304delGAGinsAAC p.E768N RefSeq GRCh38/hg38
NM_001406759.1 chr10:g.43118390_43118392delGAGinsAAC c.2302_2304delGAGinsAAC p.E768N RefSeq GRCh38/hg38
NM_001406760.1 chr10:g.43118390_43118392delGAGinsAAC c.2302_2304delGAGinsAAC p.E768N RefSeq GRCh38/hg38
NM_020630 chr10:g.43118390_43118392delGAGinsAAC c.2302_2304delGAGinsAAC p.E768N RefSeq GRCh38/hg38
NM_020975.5 chr10:g.43118390_43118392delGAGinsAAC c.2302_2304delGAGinsAAC p.E768N RefSeq GRCh38/hg38
NM_001406743.1 chr10:g.43118390_43118392delGAGinsAAC c.2302_2304delGAGinsAAC p.E768N RefSeq GRCh38/hg38

Filtering

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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References