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Gene BRAF
Variant K601del
Impact List deletion
Protein Effect unknown
Gene Variant Descriptions BRAF K601del results in the deletion of an amino acid in the protein kinase domain of the Braf protein at amino acid 601 (UniProt.org). K601del has been identified in sequencing studies (PMID: 19152441), but has not been biochemically characterized and therefore, its effect on Braf protein function is unknown (PubMed, Aug 2024).
Associated Drug Resistance
Category Variants Paths

BRAF mutant BRAF K601del

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Transcript NM_004333.6
gDNA chr7:g.140753332_140753334delTTT
cDNA c.1801_1803delAAA
Protein p.K601del
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001354609.2 chr7:g.140753332_140753334delTTT c.1801_1803delAAA p.K601del RefSeq GRCh38/hg38
NM_001378468.1 chr7:g.140753332_140753334delTTT c.1801_1803delAAA p.K601del RefSeq GRCh38/hg38
NM_004333.6 chr7:g.140753332_140753334delTTT c.1801_1803delAAA p.K601del RefSeq GRCh38/hg38
NM_001378474.1 chr7:g.140753332_140753334delTTT c.1801_1803delAAA p.K601del RefSeq GRCh38/hg38

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  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries