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Gene BRAF
Variant W604del
Impact List deletion
Protein Effect unknown
Gene Variant Descriptions BRAF W604del results in the deletion of an amino acid in the protein kinase domain of the Braf protein at amino acid 604 (UniProt.org). W604del has been identified in sequencing studies (PMID: 15513360), but has not been biochemically characterized and therefore, its effect on Braf protein function is unknown (PubMed, Sep 2024).
Associated Drug Resistance
Category Variants Paths

BRAF mutant BRAF W604del

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Transcript NM_004333.6
gDNA chr7:g.140753323_140753325delCCA
cDNA c.1810_1812delTGG
Protein p.W604del
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_004333.6 chr7:g.140753323_140753325delCCA c.1810_1812delTGG p.W604del RefSeq GRCh38/hg38
NM_001354609.2 chr7:g.140753323_140753325delCCA c.1810_1812delTGG p.W604del RefSeq GRCh38/hg38
NM_001378468.1 chr7:g.140753323_140753325delCCA c.1810_1812delTGG p.W604del RefSeq GRCh38/hg38

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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries