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Gene BRAF
Variant Q609L
Impact List missense
Protein Effect unknown
Gene Variant Descriptions BRAF Q609L lies within the protein kinase domain of the Braf protein (UniProt.org). Q609L has been identified in the scientific literature (PMID: 31837433, PMID: 34588906), but has not been biochemically characterized and therefore, its effect on Braf protein function is unknown (PubMed, Sep 2024).
Associated Drug Resistance
Category Variants Paths

BRAF mutant BRAF Q609L

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Transcript NM_004333.6
gDNA chr7:g.140753309T>A
cDNA c.1826A>T
Protein p.Q609L
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_004333.5 chr7:g.140753309T>A c.1826A>T p.Q609L RefSeq GRCh38/hg38
NM_001378474.1 chr7:g.140753309T>A c.1826A>T p.Q609L RefSeq GRCh38/hg38
NM_004333.6 chr7:g.140753309T>A c.1826A>T p.Q609L RefSeq GRCh38/hg38
NM_001378468.1 chr7:g.140753309T>A c.1826A>T p.Q609L RefSeq GRCh38/hg38
NM_004333 chr7:g.140753309T>A c.1826A>T p.Q609L RefSeq GRCh38/hg38
NM_001354609.2 chr7:g.140753309T>A c.1826A>T p.Q609L RefSeq GRCh38/hg38
XM_005250045 chr7:g.140753309T>A c.1826A>T p.Q609L RefSeq GRCh38/hg38
NM_001354609.1 chr7:g.140753309T>A c.1826A>T p.Q609L RefSeq GRCh38/hg38

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  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References