RET G810C
Gene Variant Detail

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Gene RET
Variant G810C
Impact List missense
Protein Effect unknown
Gene Variant Descriptions RET G810C lies within the protein kinase domain of the Ret protein (UniProt.org). G810C is associated with RET inhibitor resistance in the context of RET fusions (PMID: 31988000, PMID: 33161056), but has not been biochemically characterized and therefore, its effect on Ret protein function is unknown (PubMed, Feb 2025).
Associated Drug Resistance Y
Category Variants Paths

RET mutant RET G810C

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Transcript NM_020975.6
gDNA chr10:g.43119566G>T
cDNA c.2428G>T
Protein p.G810C
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001406759.1 chr10:g.43119566G>T c.2428G>T p.G810C RefSeq GRCh38/hg38
NM_001406743.1 chr10:g.43119566G>T c.2428G>T p.G810C RefSeq GRCh38/hg38
NM_020630 chr10:g.43119566G>T c.2428G>T p.G810C RefSeq GRCh38/hg38
NM_001406760.1 chr10:g.43119566G>T c.2428G>T p.G810C RefSeq GRCh38/hg38
NM_020975.5 chr10:g.43119566G>T c.2428G>T p.G810C RefSeq GRCh38/hg38
NM_020975.6 chr10:g.43119566G>T c.2428G>T p.G810C RefSeq GRCh38/hg38
NM_020630.5 chr10:g.43119566G>T c.2428G>T p.G810C RefSeq GRCh38/hg38
NM_020975 chr10:g.43119566G>T c.2428G>T p.G810C RefSeq GRCh38/hg38
NM_020630.7 chr10:g.43119566G>T c.2428G>T p.G810C RefSeq GRCh38/hg38
NM_001406744.1 chr10:g.43119566G>T c.2428G>T p.G810C RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries