Gene Variant Detail

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Gene BRAF
Variant S607P
Impact List missense
Protein Effect no effect - predicted
Gene Variant Descriptions BRAF S607P lies within the protein kinase domain of the Braf protein (UniProt.org). S607P results in Erk1/2 and Braf phosphorylation similar to wild-type Braf (PMID: 32059434), and therefore, is predicted to have no effect on Braf protein function.
Associated Drug Resistance
Category Variants Paths

BRAF mutant BRAF S607P

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Transcript NM_004333.6
gDNA chr7:g.140753316A>G
cDNA c.1819T>C
Protein p.S607P
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_005250045 chr7:g.140753316A>G c.1819T>C p.S607P RefSeq GRCh38/hg38
NM_004333 chr7:g.140753316A>G c.1819T>C p.S607P RefSeq GRCh38/hg38
NM_004333.5 chr7:g.140753316A>G c.1819T>C p.S607P RefSeq GRCh38/hg38
NM_004333.6 chr7:g.140753316A>G c.1819T>C p.S607P RefSeq GRCh38/hg38
NM_001378468.1 chr7:g.140753316A>G c.1819T>C p.S607P RefSeq GRCh38/hg38
NM_001354609.2 chr7:g.140753316A>G c.1819T>C p.S607P RefSeq GRCh38/hg38
NM_001354609.1 chr7:g.140753316A>G c.1819T>C p.S607P RefSeq GRCh38/hg38
NM_001378474.1 chr7:g.140753316A>G c.1819T>C p.S607P RefSeq GRCh38/hg38

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries