BRAF S602T
Gene Variant Detail

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Gene BRAF
Variant S602T
Impact List missense
Protein Effect unknown
Gene Variant Descriptions BRAF S602T lies within the protein kinase domain of the Braf protein (UniProt.org). S602T has been identified in sequencing studies (PMID: 24433452, PMID: 31980996), but has not been biochemically characterized and therefore, its effect on Braf protein function is unknown (PubMed, Dec 2025).
Associated Drug Resistance
Category Variants Paths

BRAF mutant BRAF S602T

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Transcript NM_004333.6
gDNA chr7:g.140753331A>T
cDNA c.1804T>A
Protein p.S602T
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001378468.1 chr7:g.140753331A>T c.1804T>A p.S602T RefSeq GRCh38/hg38
NM_001354609.2 chr7:g.140753331A>T c.1804T>A p.S602T RefSeq GRCh38/hg38
NM_004333.6 chr7:g.140753331A>T c.1804T>A p.S602T RefSeq GRCh38/hg38
NM_004333 chr7:g.140753331A>T c.1804T>A p.S602T RefSeq GRCh38/hg38
NM_004333.5 chr7:g.140753331A>T c.1804T>A p.S602T RefSeq GRCh38/hg38
NM_001378474.1 chr7:g.140753331A>T c.1804T>A p.S602T RefSeq GRCh38/hg38
XM_047420766.1 chr7:g.140753295A>T c.1804T>A p.S602T RefSeq GRCh38/hg38
XM_005250045 chr7:g.140753331A>T c.1804T>A p.S602T RefSeq GRCh38/hg38
NM_001354609.1 chr7:g.140753331A>T c.1804T>A p.S602T RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References