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Gene | BRAF |
Variant | S602T |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | BRAF S602T lies within the protein kinase domain of the Braf protein (UniProt.org). S602T has been identified in sequencing studies (PMID: 24433452, PMID: 31980996), but has not been biochemically characterized and therefore, its effect on Braf protein function is unknown (PubMed, Jun 2025). |
Associated Drug Resistance | |
Category Variants Paths |
BRAF mutant BRAF S602T |
Transcript | NM_004333.6 |
gDNA | chr7:g.140753331A>T |
cDNA | c.1804T>A |
Protein | p.S602T |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |