Gene Variant Detail

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Gene RET
Variant G10C
Impact List missense
Protein Effect unknown
Gene Variant Descriptions RET G10C lies within the signal peptide region of the Ret protein (UniProt.org). G10C has been identified in the scientific literature (PMID: 32094155), but has not been biochemically characterized and therefore, its effect on Ret protein function is unknown (PubMed, Aug 2024).
Associated Drug Resistance
Category Variants Paths

RET mutant RET G10C

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Transcript NM_020975.6
gDNA chr10:g.43077286_43077288delGGGinsTGT
cDNA c.28_30delGGGinsTGT
Protein p.G10C
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001406766.1 chr10:g.43077286_43077288delGGGinsTGT c.28_30delGGGinsTGT p.G10C RefSeq GRCh38/hg38
NM_001406778.1 chr10:g.43077286_43077288delGGGinsTGT c.28_30delGGGinsTGT p.G10C RefSeq GRCh38/hg38
NM_001406780.1 chr10:g.43077286_43077288delGGGinsTGT c.28_30delGGGinsTGT p.G10C RefSeq GRCh38/hg38
NM_001406779.1 chr10:g.43077286_43077288delGGGinsTGT c.28_30delGGGinsTGT p.G10C RefSeq GRCh38/hg38
NM_001406784.1 chr10:g.43077286_43077288delGGGinsTGT c.28_30delGGGinsTGT p.G10C RefSeq GRCh38/hg38
NM_001406792.1 chr10:g.43077286_43077288delGGGinsTGT c.28_30delGGGinsTGT p.G10C RefSeq GRCh38/hg38
NM_001406777.1 chr10:g.43077286_43077288delGGGinsTGT c.28_30delGGGinsTGT p.G10C RefSeq GRCh38/hg38
NM_001406760.1 chr10:g.43077286_43077288delGGGinsTGT c.28_30delGGGinsTGT p.G10C RefSeq GRCh38/hg38
NM_001406781.1 chr10:g.43077286_43077288delGGGinsTGT c.28_30delGGGinsTGT p.G10C RefSeq GRCh38/hg38
NM_001406743.1 chr10:g.43077286_43077288delGGGinsTGT c.28_30delGGGinsTGT p.G10C RefSeq GRCh38/hg38
NM_001406759.1 chr10:g.43077286_43077288delGGGinsTGT c.28_30delGGGinsTGT p.G10C RefSeq GRCh38/hg38
NM_001406791.1 chr10:g.43077286_43077288delGGGinsTGT c.28_30delGGGinsTGT p.G10C RefSeq GRCh38/hg38
NM_001406761.1 chr10:g.43077286_43077288delGGGinsTGT c.28_30delGGGinsTGT p.G10C RefSeq GRCh38/hg38
NM_001406775.1 chr10:g.43077286_43077288delGGGinsTGT c.28_30delGGGinsTGT p.G10C RefSeq GRCh38/hg38
NM_001406769.1 chr10:g.43077286_43077288delGGGinsTGT c.28_30delGGGinsTGT p.G10C RefSeq GRCh38/hg38
NM_001406790.1 chr10:g.43077286_43077288delGGGinsTGT c.28_30delGGGinsTGT p.G10C RefSeq GRCh38/hg38
NM_020630.7 chr10:g.43077286_43077288delGGGinsTGT c.28_30delGGGinsTGT p.G10C RefSeq GRCh38/hg38
NM_001406793.1 chr10:g.43077286_43077288delGGGinsTGT c.28_30delGGGinsTGT p.G10C RefSeq GRCh38/hg38
NM_001406762.1 chr10:g.43077286_43077288delGGGinsTGT c.28_30delGGGinsTGT p.G10C RefSeq GRCh38/hg38
NM_001406788.1 chr10:g.43077286_43077288delGGGinsTGT c.28_30delGGGinsTGT p.G10C RefSeq GRCh38/hg38
NM_001406786.1 chr10:g.43077286_43077288delGGGinsTGT c.28_30delGGGinsTGT p.G10C RefSeq GRCh38/hg38
NM_001406774.1 chr10:g.43077286_43077288delGGGinsTGT c.28_30delGGGinsTGT p.G10C RefSeq GRCh38/hg38
NM_020630.5 chr10:g.43077286_43077288delGGGinsTGT c.28_30delGGGinsTGT p.G10C RefSeq GRCh38/hg38
NM_001406764.1 chr10:g.43077286_43077288delGGGinsTGT c.28_30delGGGinsTGT p.G10C RefSeq GRCh38/hg38
NM_001406771.1 chr10:g.43077286_43077288delGGGinsTGT c.28_30delGGGinsTGT p.G10C RefSeq GRCh38/hg38
NM_001406763.1 chr10:g.43077286_43077288delGGGinsTGT c.28_30delGGGinsTGT p.G10C RefSeq GRCh38/hg38
NM_001406794.1 chr10:g.43077286_43077288delGGGinsTGT c.28_30delGGGinsTGT p.G10C RefSeq GRCh38/hg38
NM_001406782.1 chr10:g.43077286_43077288delGGGinsTGT c.28_30delGGGinsTGT p.G10C RefSeq GRCh38/hg38
NM_001406776.1 chr10:g.43077286_43077288delGGGinsTGT c.28_30delGGGinsTGT p.G10C RefSeq GRCh38/hg38
NM_001406783.1 chr10:g.43077286_43077288delGGGinsTGT c.28_30delGGGinsTGT p.G10C RefSeq GRCh38/hg38
NM_001406773.1 chr10:g.43077286_43077288delGGGinsTGT c.28_30delGGGinsTGT p.G10C RefSeq GRCh38/hg38
NM_001406787.1 chr10:g.43077286_43077288delGGGinsTGT c.28_30delGGGinsTGT p.G10C RefSeq GRCh38/hg38
NM_001406789.1 chr10:g.43077286_43077288delGGGinsTGT c.28_30delGGGinsTGT p.G10C RefSeq GRCh38/hg38
NM_001406744.1 chr10:g.43077286_43077288delGGGinsTGT c.28_30delGGGinsTGT p.G10C RefSeq GRCh38/hg38
NM_001406785.1 chr10:g.43077286_43077288delGGGinsTGT c.28_30delGGGinsTGT p.G10C RefSeq GRCh38/hg38
NM_020975.6 chr10:g.43077286_43077288delGGGinsTGT c.28_30delGGGinsTGT p.G10C RefSeq GRCh38/hg38
NM_020630 chr10:g.43077286_43077288delGGGinsTGT c.28_30delGGGinsTGT p.G10C RefSeq GRCh38/hg38
NM_001406767.1 chr10:g.43077286_43077288delGGGinsTGT c.28_30delGGGinsTGT p.G10C RefSeq GRCh38/hg38
NM_020975.5 chr10:g.43077286_43077288delGGGinsTGT c.28_30delGGGinsTGT p.G10C RefSeq GRCh38/hg38
NM_001406765.1 chr10:g.43077286_43077288delGGGinsTGT c.28_30delGGGinsTGT p.G10C RefSeq GRCh38/hg38
NM_001406772.1 chr10:g.43077286_43077288delGGGinsTGT c.28_30delGGGinsTGT p.G10C RefSeq GRCh38/hg38
NM_001406770.1 chr10:g.43077286_43077288delGGGinsTGT c.28_30delGGGinsTGT p.G10C RefSeq GRCh38/hg38
NM_001406768.1 chr10:g.43077286_43077288delGGGinsTGT c.28_30delGGGinsTGT p.G10C RefSeq GRCh38/hg38
NM_020975 chr10:g.43077286_43077288delGGGinsTGT c.28_30delGGGinsTGT p.G10C RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Molecular Profile Protein Effect Treatment Approaches
RET G10C unknown