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Gene ARID2
Variant L1423fs
Impact List frameshift
Protein Effect loss of function - predicted
Gene Variant Descriptions ARID2 L1423fs results in a change in the amino acid sequence of the Arid2 protein beginning at aa 1423 of 1835, likely resulting in premature truncation of the functional protein (UniProt.org). Due to the loss of the C2H2-type zinc finger domain (PMID: 32071245), L1423fs is predicted to lead to a loss of Arid2 protein function.
Associated Drug Resistance
Category Variants Paths

ARID2 mutant ARID2 inact mut ARID2 L1423fs

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Transcript NM_152641.4
gDNA chr12:g.(45852389_45852390)
cDNA c.(4267_4266)
Protein p.L1423fs
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_047428489.1 chr12:g.(45852389_45852390) c.(4267_4266) p.L1423fs RefSeq GRCh38/hg38
NM_001347839.1 chr12:g.(45852389_45852390) c.(4267_4266) p.L1423fs RefSeq GRCh38/hg38
XM_006719272 chr12:g.(45852389_45852390) c.(4267_4266) p.L1423fs RefSeq GRCh38/hg38
NM_001347839.2 chr12:g.(45852389_45852390) c.(4267_4266) p.L1423fs RefSeq GRCh38/hg38
NM_152641 chr12:g.(45852389_45852390) c.(4267_4266) p.L1423fs RefSeq GRCh38/hg38
NM_152641.4 chr12:g.(45852389_45852390) c.(4267_4266) p.L1423fs RefSeq GRCh38/hg38
XM_006719272.4 chr12:g.(45852389_45852390) c.(4267_4266) p.L1423fs RefSeq GRCh38/hg38
NM_152641.3 chr12:g.(45852389_45852390) c.(4267_4266) p.L1423fs RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Protein Effect Treatment Approaches
ARID2 L1423fs loss of function - predicted