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Gene ARID2
Variant N67fs
Impact List frameshift
Protein Effect loss of function - predicted
Gene Variant Descriptions ARID2 N67fs results in a change in the amino acid sequence of the Arid2 protein beginning at aa 67 of 1835, likely resulting in premature truncation of the functional protein (UniProt.org). Due to the loss of the C2H2-type zinc finger domain (PMID: 32071245), N67fs is predicted to lead to a loss of Arid2 protein function.
Associated Drug Resistance
Category Variants Paths

ARID2 mutant ARID2 inact mut ARID2 N67fs

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Transcript NM_152641.4
gDNA chr12:g.(45731228_45731229)
cDNA c.(199_198)
Protein p.N67fs
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_006719272.4 chr12:g.(45731228_45731229) c.(199_198) p.N67fs RefSeq GRCh38/hg38
NM_152641 chr12:g.(45731228_45731229) c.(199_198) p.N67fs RefSeq GRCh38/hg38
NM_152641.3 chr12:g.(45731228_45731229) c.(199_198) p.N67fs RefSeq GRCh38/hg38
NM_001347839.2 chr12:g.(45731228_45731229) c.(199_198) p.N67fs RefSeq GRCh38/hg38
XM_006719272 chr12:g.(45731228_45731229) c.(199_198) p.N67fs RefSeq GRCh38/hg38
XM_047428489.1 chr12:g.(45731228_45731229) c.(199_198) p.N67fs RefSeq GRCh38/hg38
NM_001347839.1 chr12:g.(45731228_45731229) c.(199_198) p.N67fs RefSeq GRCh38/hg38
NM_152641.4 chr12:g.(45731228_45731229) c.(199_198) p.N67fs RefSeq GRCh38/hg38

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References