Gene Variant Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Gene RET
Variant W85*
Impact List nonsense
Protein Effect loss of function - predicted
Gene Variant Descriptions RET W85* results in a premature truncation of the Ret protein at amino acid 85 of 1114 (UniProt.org). Due to the loss of all known functional domains (UniProt.org), W85* is predicted to lead to a loss of Ret protein function.
Associated Drug Resistance
Category Variants Paths

RET mutant RET inact mut RET W85*

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Transcript NM_020975.6
gDNA chr10:g.43100639G>A
cDNA c.254G>A
Protein p.W85*
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001406760.1 chr10:g.43100639G>A c.254G>A p.W85* RefSeq GRCh38/hg38
NM_001406763.1 chr10:g.43100639G>A c.254G>A p.W85* RefSeq GRCh38/hg38
NM_001406780.1 chr10:g.43100639G>A c.254G>A p.W85* RefSeq GRCh38/hg38
NM_001406767.1 chr10:g.43100639G>A c.254G>A p.W85* RefSeq GRCh38/hg38
NM_001406789.1 chr10:g.43100639G>A c.254G>A p.W85* RefSeq GRCh38/hg38
NM_020975 chr10:g.43100639G>A c.254G>A p.W85* RefSeq GRCh38/hg38
NM_020630 chr10:g.43100639G>A c.254G>A p.W85* RefSeq GRCh38/hg38
NM_020975.6 chr10:g.43100639G>A c.254G>A p.W85* RefSeq GRCh38/hg38
NM_001406777.1 chr10:g.43100639G>A c.254G>A p.W85* RefSeq GRCh38/hg38
NM_001406776.1 chr10:g.43100639G>A c.254G>A p.W85* RefSeq GRCh38/hg38
NM_001406787.1 chr10:g.43100639G>A c.254G>A p.W85* RefSeq GRCh38/hg38
NM_001406785.1 chr10:g.43100639G>A c.254G>A p.W85* RefSeq GRCh38/hg38
NM_001406783.1 chr10:g.43100639G>A c.254G>A p.W85* RefSeq GRCh38/hg38
NM_001406743.1 chr10:g.43100639G>A c.254G>A p.W85* RefSeq GRCh38/hg38
NM_001406788.1 chr10:g.43100639G>A c.254G>A p.W85* RefSeq GRCh38/hg38
NM_001406744.1 chr10:g.43100639G>A c.254G>A p.W85* RefSeq GRCh38/hg38
NM_001406768.1 chr10:g.43100639G>A c.254G>A p.W85* RefSeq GRCh38/hg38
NM_001406771.1 chr10:g.43100639G>A c.254G>A p.W85* RefSeq GRCh38/hg38
NM_001406759.1 chr10:g.43100639G>A c.254G>A p.W85* RefSeq GRCh38/hg38
NM_001406766.1 chr10:g.43100639G>A c.254G>A p.W85* RefSeq GRCh38/hg38
NM_020630.5 chr10:g.43100639G>A c.254G>A p.W85* RefSeq GRCh38/hg38
NM_001406770.1 chr10:g.43100639G>A c.254G>A p.W85* RefSeq GRCh38/hg38
NM_001406769.1 chr10:g.43100639G>A c.254G>A p.W85* RefSeq GRCh38/hg38
NM_001406781.1 chr10:g.43100639G>A c.254G>A p.W85* RefSeq GRCh38/hg38
NM_020630.7 chr10:g.43100639G>A c.254G>A p.W85* RefSeq GRCh38/hg38
NM_001406778.1 chr10:g.43100639G>A c.254G>A p.W85* RefSeq GRCh38/hg38
NM_001406775.1 chr10:g.43100639G>A c.254G>A p.W85* RefSeq GRCh38/hg38
NM_001406765.1 chr10:g.43100639G>A c.254G>A p.W85* RefSeq GRCh38/hg38
NM_001406779.1 chr10:g.43100639G>A c.254G>A p.W85* RefSeq GRCh38/hg38
NM_001406786.1 chr10:g.43100639G>A c.254G>A p.W85* RefSeq GRCh38/hg38
NM_001406764.1 chr10:g.43100639G>A c.254G>A p.W85* RefSeq GRCh38/hg38
NM_001406761.1 chr10:g.43100639G>A c.254G>A p.W85* RefSeq GRCh38/hg38
NM_001406773.1 chr10:g.43100639G>A c.254G>A p.W85* RefSeq GRCh38/hg38
NM_020975.5 chr10:g.43100639G>A c.254G>A p.W85* RefSeq GRCh38/hg38
NM_001406782.1 chr10:g.43100639G>A c.254G>A p.W85* RefSeq GRCh38/hg38
NM_001406790.1 chr10:g.43100639G>A c.254G>A p.W85* RefSeq GRCh38/hg38
NM_001406772.1 chr10:g.43100639G>A c.254G>A p.W85* RefSeq GRCh38/hg38
NM_001406774.1 chr10:g.43100639G>A c.254G>A p.W85* RefSeq GRCh38/hg38
NM_001406762.1 chr10:g.43100639G>A c.254G>A p.W85* RefSeq GRCh38/hg38
NM_001406791.1 chr10:g.43100639G>A c.254G>A p.W85* RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References