Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
Gene | RET |
Variant | P1070S |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | RET P1070S lies within the cytoplasmic domain of the Ret protein (UniProt.org). P1070S has not been characterized and therefore, its effect on Ret protein function is unknown (PubMed, Feb 2024). |
Associated Drug Resistance | |
Category Variants Paths |
RET mutant RET P1070S |
Transcript | NM_020975.6 |
gDNA | chr10:g.43128132C>T |
cDNA | c.3208C>T |
Protein | p.P1070S |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
NM_020975.6 | chr10:g.43128132C>T | c.3208C>T | p.P1070S | RefSeq | GRCh38/hg38 |
NM_020975.5 | chr10:g.43128132C>T | c.3208C>T | p.P1070S | RefSeq | GRCh38/hg38 |
NM_001406743.1 | chr10:g.43128132C>T | c.3208C>T | p.P1070S | RefSeq | GRCh38/hg38 |
NM_020975 | chr10:g.43128132C>T | c.3208C>T | p.P1070S | RefSeq | GRCh38/hg38 |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|