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Gene | ABL1 |
Variant | M343T |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | ABL1 M343T lies within the protein kinase domain of the Abl1 protein (UniProt.org). M343T has been identified in the scientific literature (PMID: 23044928), but has not been biochemically characterized and therefore, its effect on Abl1 protein function is unknown (PubMed, Aug 2024). |
Associated Drug Resistance | |
Category Variants Paths |
ABL1 mutant ABL1 M343T |
Transcript | NM_005157.6 |
gDNA | chr9:g.130872980T>C |
cDNA | c.1028T>C |
Protein | p.M343T |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
NM_005157.6 | chr9:g.130872980T>C | c.1028T>C | p.M343T | RefSeq | GRCh38/hg38 |
NM_005157.5 | chr9:g.130872980T>C | c.1028T>C | p.M343T | RefSeq | GRCh38/hg38 |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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