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Gene | JAK3 |
Variant | rearrange |
Impact List | unknown |
Protein Effect | unknown |
Gene Variant Descriptions | JAK3 rearrangement indicates an unspecified rearrangement of the JAK3 gene. |
Associated Drug Resistance | |
Category Variants Paths |
JAK3 mutant JAK3 rearrange |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
JAK3 rearrange | childhood B-cell acute lymphoblastic leukemia | not applicable | N/A | Guideline | Prognostic | JAK3 rearrangements are associated with a poor prognosis in pediatric patients with B-cell acute lymphoblastic leukemia (NCCN.org). | detail... |
JAK3 rearrange | B-cell acute lymphoblastic leukemia | not applicable | N/A | Guideline | Prognostic | JAK3 rearrangements are associated with a poor prognosis in patients with B-cell acute lymphoblastic leukemia (NCCN.org). | detail... |