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Gene RET
Variant R114H
Impact List missense
Protein Effect unknown
Gene Variant Descriptions RET R114H lies within the extracellular domain of the Ret protein (UniProt.org). R114H has been identified in the scientific literature (PMID: 33827484, PMID: 34670378), but has not been biochemically characterized and therefore, its effect on Ret protein function is unknown (PubMed, Aug 2024).
Associated Drug Resistance
Category Variants Paths

RET mutant RET R114H

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Transcript NM_020975.6
gDNA chr10:g.43102345G>A
cDNA c.341G>A
Protein p.R114H
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001406781.1 chr10:g.43102345G>A c.341G>A p.R114H RefSeq GRCh38/hg38
NM_001406769.1 chr10:g.43102345G>A c.341G>A p.R114H RefSeq GRCh38/hg38
NM_001406772.1 chr10:g.43102345G>A c.341G>A p.R114H RefSeq GRCh38/hg38
NM_001406787.1 chr10:g.43102345G>A c.341G>A p.R114H RefSeq GRCh38/hg38
NM_020975.6 chr10:g.43102345G>A c.341G>A p.R114H RefSeq GRCh38/hg38
NM_001406765.1 chr10:g.43102345G>A c.341G>A p.R114H RefSeq GRCh38/hg38
NM_001406785.1 chr10:g.43102345G>A c.341G>A p.R114H RefSeq GRCh38/hg38
NM_001406760.1 chr10:g.43102345G>A c.341G>A p.R114H RefSeq GRCh38/hg38
NM_001355216.2 chr10:g.43109070G>A c.341G>A p.R114H RefSeq GRCh38/hg38
NM_001406743.1 chr10:g.43102345G>A c.341G>A p.R114H RefSeq GRCh38/hg38
NM_001406763.1 chr10:g.43102345G>A c.341G>A p.R114H RefSeq GRCh38/hg38
NM_001406771.1 chr10:g.43102345G>A c.341G>A p.R114H RefSeq GRCh38/hg38
NM_020975.5 chr10:g.43102345G>A c.341G>A p.R114H RefSeq GRCh38/hg38
NM_001406782.1 chr10:g.43102345G>A c.341G>A p.R114H RefSeq GRCh38/hg38
NM_001355216.1 chr10:g.43109070G>A c.341G>A p.R114H RefSeq GRCh38/hg38
NM_001406780.1 chr10:g.43102345G>A c.341G>A p.R114H RefSeq GRCh38/hg38
NM_001406773.1 chr10:g.43102345G>A c.341G>A p.R114H RefSeq GRCh38/hg38
NM_001406779.1 chr10:g.43102345G>A c.341G>A p.R114H RefSeq GRCh38/hg38
NM_020630.5 chr10:g.43102345G>A c.341G>A p.R114H RefSeq GRCh38/hg38
NM_001406744.1 chr10:g.43102345G>A c.341G>A p.R114H RefSeq GRCh38/hg38
NM_001406759.1 chr10:g.43102345G>A c.341G>A p.R114H RefSeq GRCh38/hg38
NM_020630.7 chr10:g.43102345G>A c.341G>A p.R114H RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References