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Gene | BRAF |
Variant | T119S |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | BRAF T119S does not lie within any known functional domains of the Braf protein (UniProt.org). T119S has been identified in the scientific literature (PMID: 34301793), but has not been biochemically characterized and therefore, its effect on Braf protein function is unknown (PubMed, Mar 2024). |
Associated Drug Resistance | |
Category Variants Paths |
BRAF mutant BRAF T119S |
Transcript | NM_004333.6 |
gDNA | chr7:g.140834757G>C |
cDNA | c.356C>G |
Protein | p.T119S |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
XM_017012558.1 | chr7:g.140834757G>C | c.356C>G | p.T119S | RefSeq | GRCh38/hg38 |
NM_001378468.1 | chr7:g.140834757G>C | c.356C>G | p.T119S | RefSeq | GRCh38/hg38 |
XM_017012559.2 | chr7:g.140834757G>C | c.356C>G | p.T119S | RefSeq | GRCh38/hg38 |
NM_001378474.1 | chr7:g.140834757G>C | c.356C>G | p.T119S | RefSeq | GRCh38/hg38 |
NM_004333.6 | chr7:g.140834757G>C | c.356C>G | p.T119S | RefSeq | GRCh38/hg38 |
NM_001378467.1 | chr7:g.140834757G>C | c.356C>G | p.T119S | RefSeq | GRCh38/hg38 |
NM_001378469.1 | chr7:g.140834757G>C | c.356C>G | p.T119S | RefSeq | GRCh38/hg38 |
XM_047420769.1 | chr7:g.140834757G>C | c.356C>G | p.T119S | RefSeq | GRCh38/hg38 |
XM_047420767.1 | chr7:g.140834757G>C | c.356C>G | p.T119S | RefSeq | GRCh38/hg38 |
NM_001354609.1 | chr7:g.140834757G>C | c.356C>G | p.T119S | RefSeq | GRCh38/hg38 |
NM_004333.5 | chr7:g.140834757G>C | c.356C>G | p.T119S | RefSeq | GRCh38/hg38 |
NM_001378471.1 | chr7:g.140834757G>C | c.356C>G | p.T119S | RefSeq | GRCh38/hg38 |
NM_001374244.1 | chr7:g.140834757G>C | c.356C>G | p.T119S | RefSeq | GRCh38/hg38 |
NM_001354609.2 | chr7:g.140834757G>C | c.356C>G | p.T119S | RefSeq | GRCh38/hg38 |
NM_001374258.1 | chr7:g.140834757G>C | c.356C>G | p.T119S | RefSeq | GRCh38/hg38 |
XM_017012559.1 | chr7:g.140834757G>C | c.356C>G | p.T119S | RefSeq | GRCh38/hg38 |
XM_047420768.1 | chr7:g.140834757G>C | c.356C>G | p.T119S | RefSeq | GRCh38/hg38 |
Molecular Profile | Protein Effect | Treatment Approaches |
---|---|---|
BRAF T119S | unknown | |
BRAF T119S BRAF V600E |