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Gene ALK
Variant F1245X
Impact List missense
Protein Effect unknown
Gene Variant Descriptions ALK F1245X indicates any Alk missense mutation that results in replacement of the phenylalanine (F) at amino acid 1245 by a different amino acid.
Associated Drug Resistance
Category Variants Paths

ALK mutant ALK F1245X

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Transcript NM_004304.5
gDNA chr2:g.29213992_29213994
cDNA c.3733_3735
Protein p.F1245
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_004304.4 chr2:g.29213992_29213994 c.3733_3735 p.F1245 RefSeq GRCh38/hg38
NM_004304.5 chr2:g.29213992_29213994 c.3733_3735 p.F1245 RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References