Gene Variant Detail

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Gene RET
Variant R144H
Impact List missense
Protein Effect no effect - predicted
Gene Variant Descriptions RET R144H lies within the extracellular domain of the Ret protein (UniProt.org). R144H results in phosphorylation of Ret and Erk similar to wild-type in cell culture (PMID: 26395553), and therefore, is predicted to have no effect on Ret protein function.
Associated Drug Resistance
Category Variants Paths

RET mutant RET R144H

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Transcript NM_020975.6
gDNA chr10:g.43102435G>A
cDNA c.431G>A
Protein p.R144H
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001406780.1 chr10:g.43102435G>A c.431G>A p.R144H RefSeq GRCh38/hg38
NM_001406779.1 chr10:g.43102435G>A c.431G>A p.R144H RefSeq GRCh38/hg38
NM_020975.5 chr10:g.43102435G>A c.431G>A p.R144H RefSeq GRCh38/hg38
NM_020630.7 chr10:g.43102435G>A c.431G>A p.R144H RefSeq GRCh38/hg38
NM_001406744.1 chr10:g.43102435G>A c.431G>A p.R144H RefSeq GRCh38/hg38
NM_001406759.1 chr10:g.43102435G>A c.431G>A p.R144H RefSeq GRCh38/hg38
NM_001406760.1 chr10:g.43102435G>A c.431G>A p.R144H RefSeq GRCh38/hg38
NM_001406782.1 chr10:g.43102435G>A c.431G>A p.R144H RefSeq GRCh38/hg38
NM_001406784.1 chr10:g.43111364_43111365delGGinsAT c.431_432delGGinsAT p.R144H RefSeq GRCh38/hg38
NM_001406763.1 chr10:g.43102435G>A c.431G>A p.R144H RefSeq GRCh38/hg38
NM_020630.5 chr10:g.43102435G>A c.431G>A p.R144H RefSeq GRCh38/hg38
NM_001406743.1 chr10:g.43102435G>A c.431G>A p.R144H RefSeq GRCh38/hg38
NM_001406769.1 chr10:g.43102435G>A c.431G>A p.R144H RefSeq GRCh38/hg38
NM_001406781.1 chr10:g.43102435G>A c.431G>A p.R144H RefSeq GRCh38/hg38
NM_001406765.1 chr10:g.43102435G>A c.431G>A p.R144H RefSeq GRCh38/hg38
NM_020975.6 chr10:g.43102435G>A c.431G>A p.R144H RefSeq GRCh38/hg38
NM_001406771.1 chr10:g.43102435G>A c.431G>A p.R144H RefSeq GRCh38/hg38
NM_001406787.1 chr10:g.43102435G>A c.431G>A p.R144H RefSeq GRCh38/hg38
NM_001406773.1 chr10:g.43102435G>A c.431G>A p.R144H RefSeq GRCh38/hg38
NM_001406785.1 chr10:g.43102435G>A c.431G>A p.R144H RefSeq GRCh38/hg38
NM_001406772.1 chr10:g.43102435G>A c.431G>A p.R144H RefSeq GRCh38/hg38

Filtering

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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  • Click on any column header arrows to sort by that column
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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries