ABL1 H295dup
Gene Variant Detail

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Gene ABL1
Variant H295dup
Impact List duplication
Protein Effect unknown
Gene Variant Descriptions ABL1 H295dup indicates the insertion of the duplicate amino acid, histidine (H)-295, in the protein kinase domain of the Abl1 protein (UniProt.org). H295dup has been identified in sequencing studies (PMID: 21442193), but has not been biochemically characterized and therefore, its effect on Abl1 protein function is unknown (PubMed, Mar 2026).
Associated Drug Resistance
Category Variants Paths

ABL1 mutant ABL1 H295dup

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Transcript NM_005157.6
gDNA chr9:g.130872189_130872191
cDNA c.883_885
Protein p.H295
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_005157.6 chr9:g.130872189_130872191 c.883_885 p.H295 RefSeq GRCh38/hg38
NM_005157.5 chr9:g.130872190_130872191insTCA c.884_885insTCA p.H295dup RefSeq GRCh38/hg38

Filtering

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  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References