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Gene RET
Variant R177W
Impact List missense
Protein Effect unknown
Gene Variant Descriptions RET R177W lies within the cadherin domain of the Ret protein (UniProt.org). R177W has been identified in sequencing studies (PMID: 34741450, PMID: 32284345), but has not been biochemically characterized and therefore, its effect on Ret protein function is unknown (PubMed, Aug 2024).
Associated Drug Resistance
Category Variants Paths

RET mutant RET R177W

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Transcript NM_020975.6
gDNA chr10:g.43102533C>T
cDNA c.529C>T
Protein p.R177W
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001406771.1 chr10:g.43102533C>T c.529C>T p.R177W RefSeq GRCh38/hg38
NM_001406760.1 chr10:g.43102533C>T c.529C>T p.R177W RefSeq GRCh38/hg38
NM_020630.5 chr10:g.43102533C>T c.529C>T p.R177W RefSeq GRCh38/hg38
NM_020630.7 chr10:g.43102533C>T c.529C>T p.R177W RefSeq GRCh38/hg38
NM_001406780.1 chr10:g.43102533C>T c.529C>T p.R177W RefSeq GRCh38/hg38
NM_001406763.1 chr10:g.43102533C>T c.529C>T p.R177W RefSeq GRCh38/hg38
NM_001406773.1 chr10:g.43102533C>T c.529C>T p.R177W RefSeq GRCh38/hg38
NM_001406743.1 chr10:g.43102533C>T c.529C>T p.R177W RefSeq GRCh38/hg38
NM_001406744.1 chr10:g.43102533C>T c.529C>T p.R177W RefSeq GRCh38/hg38
NM_020975.5 chr10:g.43102533C>T c.529C>T p.R177W RefSeq GRCh38/hg38
NM_020975.6 chr10:g.43102533C>T c.529C>T p.R177W RefSeq GRCh38/hg38
NM_001406772.1 chr10:g.43102533C>T c.529C>T p.R177W RefSeq GRCh38/hg38
NM_001406787.1 chr10:g.43102533C>T c.529C>T p.R177W RefSeq GRCh38/hg38
NM_001406769.1 chr10:g.43102533C>T c.529C>T p.R177W RefSeq GRCh38/hg38
NM_001406779.1 chr10:g.43102533C>T c.529C>T p.R177W RefSeq GRCh38/hg38
NM_001406781.1 chr10:g.43102533C>T c.529C>T p.R177W RefSeq GRCh38/hg38
NM_001406759.1 chr10:g.43102533C>T c.529C>T p.R177W RefSeq GRCh38/hg38
NM_001406785.1 chr10:g.43102533C>T c.529C>T p.R177W RefSeq GRCh38/hg38
NM_001406765.1 chr10:g.43102533C>T c.529C>T p.R177W RefSeq GRCh38/hg38
NM_001406782.1 chr10:g.43102533C>T c.529C>T p.R177W RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries