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Gene RET
Variant E623G
Impact List missense
Protein Effect unknown
Gene Variant Descriptions RET E623G lies within the extracellular domain of the Ret protein (UniProt.org). E623G has been identified in sequencing studies (PMID: 34741450), but has not been biochemically characterized and therefore, its effect on Ret protein function is unknown (PubMed, Aug 2024).
Associated Drug Resistance
Category Variants Paths

RET mutant RET E623G

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Transcript NM_020975.6
gDNA chr10:g.43113664A>G
cDNA c.1868A>G
Protein p.E623G
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_020630.5 chr10:g.43113664A>G c.1868A>G p.E623G RefSeq GRCh38/hg38
NM_001406743.1 chr10:g.43113664A>G c.1868A>G p.E623G RefSeq GRCh38/hg38
NM_001406760.1 chr10:g.43113664A>G c.1868A>G p.E623G RefSeq GRCh38/hg38
NM_001406763.1 chr10:g.43113664A>G c.1868A>G p.E623G RefSeq GRCh38/hg38
NM_001406791.1 chr10:g.43126708A>G c.1868A>G p.E623G RefSeq GRCh38/hg38
NM_020630.7 chr10:g.43113664A>G c.1868A>G p.E623G RefSeq GRCh38/hg38
NM_020975.6 chr10:g.43113664A>G c.1868A>G p.E623G RefSeq GRCh38/hg38
NM_020975.5 chr10:g.43113664A>G c.1868A>G p.E623G RefSeq GRCh38/hg38
NM_001406765.1 chr10:g.43113664A>G c.1868A>G p.E623G RefSeq GRCh38/hg38
NM_001406744.1 chr10:g.43113664A>G c.1868A>G p.E623G RefSeq GRCh38/hg38
NM_001406759.1 chr10:g.43113664A>G c.1868A>G p.E623G RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Protein Effect Treatment Approaches
RET E623G unknown