RET K662M
Gene Variant Detail

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Gene RET
Variant K662M
Impact List missense
Protein Effect unknown
Gene Variant Descriptions RET K662M lies within the cytoplasmic domain of the Ret protein (UniProt.org). K662M has been identified in sequencing studies (PMID: 34741450, PMID: 32284345), but has not been biochemically characterized and therefore, its effect on Ret protein function is unknown (PubMed, Nov 2025).
Associated Drug Resistance
Category Variants Paths

RET mutant RET K662M

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Transcript NM_020975.6
gDNA chr10:g.43114585A>T
cDNA c.1985A>T
Protein p.K662M
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_020630.7 chr10:g.43114585A>T c.1985A>T p.K662M RefSeq GRCh38/hg38
NM_001406766.1 chr10:g.43116720A>T c.1985A>T p.K662M RefSeq GRCh38/hg38
NM_001406771.1 chr10:g.43119561_43119562delAAinsTG c.1985_1986delAAinsTG p.K662M RefSeq GRCh38/hg38
NM_001406770.1 chr10:g.43116720A>T c.1985A>T p.K662M RefSeq GRCh38/hg38
NM_001355216.2 chr10:g.43121962_43121963delAAinsTG c.1985_1986delAAinsTG p.K662M RefSeq GRCh38/hg38
NM_020975.5 chr10:g.43114585A>T c.1985A>T p.K662M RefSeq GRCh38/hg38
NM_001406743.1 chr10:g.43114585A>T c.1985A>T p.K662M RefSeq GRCh38/hg38
NM_001406760.1 chr10:g.43114585A>T c.1985A>T p.K662M RefSeq GRCh38/hg38
NM_001406773.1 chr10:g.43119561_43119562delAAinsTG c.1985_1986delAAinsTG p.K662M RefSeq GRCh38/hg38
NM_020630.5 chr10:g.43114585A>T c.1985A>T p.K662M RefSeq GRCh38/hg38
NM_001406744.1 chr10:g.43114585A>T c.1985A>T p.K662M RefSeq GRCh38/hg38
NM_001406767.1 chr10:g.43116720A>T c.1985A>T p.K662M RefSeq GRCh38/hg38
NM_020975.6 chr10:g.43114585A>T c.1985A>T p.K662M RefSeq GRCh38/hg38
NM_001406759.1 chr10:g.43114585A>T c.1985A>T p.K662M RefSeq GRCh38/hg38

Filtering

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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Protein Effect Treatment Approaches
RET K662M unknown