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Gene | ALK |
Variant | G1202L |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | ALK G1202L lies within the protein kinase domain of the Alk protein (UniProt.org). G1202L has been identified in the scientific literature (PMID: 33380260), but has not been biochemically characterized and therefore, its effect on Alk protein function is unknown (PubMed, Apr 2024). |
Associated Drug Resistance | |
Category Variants Paths |
ALK mutant ALK G1202X ALK G1202L |
Transcript | NM_004304.5 |
gDNA | chr2:g.29220746_29220747delGGinsCT |
cDNA | c.3604_3605delGGinsCT |
Protein | p.G1202L |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
NM_004304.5 | chr2:g.29220746_29220747delGGinsCT | c.3604_3605delGGinsCT | p.G1202L | RefSeq | GRCh38/hg38 |
NM_004304.4 | chr2:g.29220746_29220747delGGinsCT | c.3604_3605delGGinsCT | p.G1202L | RefSeq | GRCh38/hg38 |
Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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