RET E632_C634del
Gene Variant Detail

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Gene RET
Variant E632_C634del
Impact List deletion
Protein Effect unknown
Gene Variant Descriptions RET E632_C634del results in the deletion of three amino acids in the extracellular domain of the Ret protein from amino acids 632 to 634 (UniProt.org). E632_C634del has been identified in the scientific literature (PMID: 35616103, PMID: 31605946), but has not been biochemically characterized and therefore, its effect on Ret protein function is unknown (PubMed, Jul 2025).
Associated Drug Resistance
Category Variants Paths

RET mutant RET E632_C634del

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Transcript NM_020975.6
gDNA chr10:g.43114494_43114502delGAGCTGTGC
cDNA c.1894_1902delGAGCTGTGC
Protein p.E632_C634del
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001406743.1 chr10:g.43114494_43114502delGAGCTGTGC c.1894_1902delGAGCTGTGC p.E632_C634del RefSeq GRCh38/hg38
NM_020975.5 chr10:g.43114494_43114502delGAGCTGTGC c.1894_1902delGAGCTGTGC p.E632_C634del RefSeq GRCh38/hg38
NM_020630.7 chr10:g.43114494_43114502delGAGCTGTGC c.1894_1902delGAGCTGTGC p.E632_C634del RefSeq GRCh38/hg38
NM_001406759.1 chr10:g.43114494_43114502delGAGCTGTGC c.1894_1902delGAGCTGTGC p.E632_C634del RefSeq GRCh38/hg38
NM_020975.6 chr10:g.43114494_43114502delGAGCTGTGC c.1894_1902delGAGCTGTGC p.E632_C634del RefSeq GRCh38/hg38
NM_001406744.1 chr10:g.43114494_43114502delGAGCTGTGC c.1894_1902delGAGCTGTGC p.E632_C634del RefSeq GRCh38/hg38
NM_001406760.1 chr10:g.43114494_43114502delGAGCTGTGC c.1894_1902delGAGCTGTGC p.E632_C634del RefSeq GRCh38/hg38
NM_020630.5 chr10:g.43114494_43114502delGAGCTGTGC c.1894_1902delGAGCTGTGC p.E632_C634del RefSeq GRCh38/hg38

Filtering

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  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
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Sorting

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References