Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
Gene | RET |
Variant | V899_E902del |
Impact List | deletion |
Protein Effect | unknown |
Gene Variant Descriptions | RET V899_E902del results in the deletion of four amino acids in the protein kinase domain of the Ret protein from amino acids 899 to 902 (UniProt.org). V899_E902del has been identified in the scientific literature (PMID: 35616103), but has not been biochemically characterized and therefore, its effect on Ret protein function is unknown (PubMed, Jan 2025). |
Associated Drug Resistance | |
Category Variants Paths |
RET mutant RET V899_E902del |
Transcript | NM_020975.6 |
gDNA | chr10:g.43120169_43120180del12 |
cDNA | c.2696_2707del12 |
Protein | p.V899_E902del |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
NM_020630.5 | chr10:g.43120169_43120180del12 | c.2696_2707del12 | p.V899_E902del | RefSeq | GRCh38/hg38 |
NM_001406759.1 | chr10:g.43120169_43120180del12 | c.2696_2707del12 | p.V899_E902del | RefSeq | GRCh38/hg38 |
NM_001406743.1 | chr10:g.43120169_43120180del12 | c.2696_2707del12 | p.V899_E902del | RefSeq | GRCh38/hg38 |
NM_001406760.1 | chr10:g.43120169_43120180del12 | c.2696_2707del12 | p.V899_E902del | RefSeq | GRCh38/hg38 |
NM_001406744.1 | chr10:g.43120169_43120180del12 | c.2696_2707del12 | p.V899_E902del | RefSeq | GRCh38/hg38 |
NM_020630.7 | chr10:g.43120169_43120180del12 | c.2696_2707del12 | p.V899_E902del | RefSeq | GRCh38/hg38 |
NM_020975.5 | chr10:g.43120169_43120180del12 | c.2696_2707del12 | p.V899_E902del | RefSeq | GRCh38/hg38 |
NM_020975.6 | chr10:g.43120169_43120180del12 | c.2696_2707del12 | p.V899_E902del | RefSeq | GRCh38/hg38 |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|