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RET V591_G607del - Gene Variant Detail

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Gene RET
Variant V591_G607del
Impact List deletion
Protein Effect unknown
Gene Variant Descriptions RET V591_G607del results in the deletion of 17 amino acids in the extracellular domain of the Ret protein from amino acids 591 to 607 (UniProt.org). V591_G607del has been identified in the scientific literature (PMID: 36053791), but has not been biochemically characterized and therefore, its effect on Ret protein function is unknown (PubMed, Jan 2025).
Associated Drug Resistance
Category Variants Paths

RET mutant RET V591_G607del

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Transcript NM_020975.6
gDNA chr10:g.43113567_43113617del51
cDNA c.1771_1821del51
Protein p.V591_G607del
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001406744.1 chr10:g.43113567_43113617del51 c.1771_1821del51 p.V591_G607del RefSeq GRCh38/hg38
NM_001406759.1 chr10:g.43113567_43113617del51 c.1771_1821del51 p.V591_G607del RefSeq GRCh38/hg38
NM_020630.5 chr10:g.43113567_43113617del51 c.1771_1821del51 p.V591_G607del RefSeq GRCh38/hg38
NM_001406760.1 chr10:g.43113567_43113617del51 c.1771_1821del51 p.V591_G607del RefSeq GRCh38/hg38
NM_001406765.1 chr10:g.43113567_43113617del51 c.1771_1821del51 p.V591_G607del RefSeq GRCh38/hg38
NM_020630.7 chr10:g.43113567_43113617del51 c.1771_1821del51 p.V591_G607del RefSeq GRCh38/hg38
NM_020975.6 chr10:g.43113567_43113617del51 c.1771_1821del51 p.V591_G607del RefSeq GRCh38/hg38
NM_001406743.1 chr10:g.43113567_43113617del51 c.1771_1821del51 p.V591_G607del RefSeq GRCh38/hg38
NM_020975.5 chr10:g.43113567_43113617del51 c.1771_1821del51 p.V591_G607del RefSeq GRCh38/hg38
NM_001406763.1 chr10:g.43113567_43113617del51 c.1771_1821del51 p.V591_G607del RefSeq GRCh38/hg38

Filtering

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries