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Gene | ALK |
Variant | E1129V |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | ALK E1129V lies within the protein kinase domain of the Alk protein (UniProt.org). E1129V has been identified in the scientific literature (PMID: 34890832, PMID: 36093526, PMID: 33161228), but has not been biochemically characterized and therefore, its effect on Alk protein function is unknown (PubMed, Apr 2024). |
Associated Drug Resistance | |
Category Variants Paths |
ALK mutant ALK E1129V |
Transcript | NM_004304.5 |
gDNA | chr2:g.29222581T>A |
cDNA | c.3386A>T |
Protein | p.E1129V |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
NM_004304.4 | chr2:g.29222581T>A | c.3386A>T | p.E1129V | RefSeq | GRCh38/hg38 |
NM_004304.5 | chr2:g.29222581T>A | c.3386A>T | p.E1129V | RefSeq | GRCh38/hg38 |
Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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