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Gene | BRAF |
Variant | T470R |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | BRAF T470R lies within the protein kinase domain of the Braf protein (UniProt.org). T470R has been identified in the scientific literature (PMID: 33861486), but has not been biochemically characterized and therefore, its effect on Braf protein function is unknown (PubMed, Sep 2024). |
Associated Drug Resistance | |
Category Variants Paths |
BRAF mutant BRAF T470R |
Transcript | NM_004333.6 |
gDNA | chr7:g.140781599G>C |
cDNA | c.1409C>G |
Protein | p.T470R |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
NM_001354609.1 | chr7:g.140781599G>C | c.1409C>G | p.T470R | RefSeq | GRCh38/hg38 |
XM_047420769.1 | chr7:g.140781599G>C | c.1409C>G | p.T470R | RefSeq | GRCh38/hg38 |
NM_004333.6 | chr7:g.140781599G>C | c.1409C>G | p.T470R | RefSeq | GRCh38/hg38 |
NM_001378474.1 | chr7:g.140781599G>C | c.1409C>G | p.T470R | RefSeq | GRCh38/hg38 |
NM_001378468.1 | chr7:g.140781599G>C | c.1409C>G | p.T470R | RefSeq | GRCh38/hg38 |
NM_001354609.2 | chr7:g.140781599G>C | c.1409C>G | p.T470R | RefSeq | GRCh38/hg38 |
NM_004333.5 | chr7:g.140781599G>C | c.1409C>G | p.T470R | RefSeq | GRCh38/hg38 |
Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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