Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
Gene | NTRK2 |
Variant | H245Y |
Impact List | missense |
Protein Effect | no effect - predicted |
Gene Variant Descriptions | NTRK2 H245Y lies within Ig-like C2-type domain 1 of the Ntrk2 protein (UniProt.org). H245Y does not induce IL-3 independent growth in cultured cells (PMID: 32315394), and therefore, is predicted to have no effect on Ntrk2 protein function. |
Associated Drug Resistance | |
Category Variants Paths |
NTRK2 mutant NTRK2 H245Y |
Transcript | NM_001018064.3 |
gDNA | chr9:g.84724236C>T |
cDNA | c.733C>T |
Protein | p.H245Y |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |